hnRNP R
Component of ribonucleosomes, which are complexes of at least 20 other different heterogenious nuclear ribonucleoproteins (hnRNP). hnRNP play an important role in processing of precursor mRNA in the nucleus. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: RNA splicing; RNA-binding; Spliceosome |
Chromosomal Location of human Ortholog: 1p36.12 |
Cellular Component:
axon terminus; catalytic step 2 spliceosome; dendrite; endoplasmic reticulum; growth cone; nucleolus; nucleoplasm; nucleus; ribonucleoprotein complex; spliceosomal complex
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Molecular Function:
mRNA 3'-UTR binding; mRNA binding; protein binding; RNA binding
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Biological Process:
circadian rhythm; mRNA destabilization; mRNA processing; mRNA splicing, via spliceosome; negative regulation of catalytic activity
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Disease: Neurodevelopmental Disorder With Dysmorphic Facies And Skeletal And Brain Abnormalities
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Reference #:
O43390
(UniProtKB)
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Alt. Names/Synonyms: FLJ25714; Heterogeneous nuclear ribonucleoprotein R; hnRNP R; hnRNP-R; HNRNPR; HNRPR
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Gene Symbols: HNRNPR
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Molecular weight:
70,943 Da
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Basal Isoelectric point:
8.23
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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