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SRPR
Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Belongs to the GTP-binding SRP family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Endoplasmic reticulum |
| Chromosomal Location of human Ortholog: 11q24.2 |
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Cellular Component:
endoplasmic reticulum membrane; membrane; signal recognition particle receptor complex
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Molecular Function:
GTP binding; GTPase activity; molecular adaptor activity; signal recognition particle binding
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Biological Process:
cotranslational protein targeting to membrane; protein targeting to ER; SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
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Reference #:
P08240
(UniProtKB)
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Alt. Names/Synonyms: Docking protein alpha; DP; DP-alpha; MGC17355; MGC3650; MGC9571; signal recognition particle receptor (docking protein); Signal recognition particle receptor subunit alpha; SR-alpha; Sralpha; SRP receptor alpha subunit; SRP receptor subunit alpha; SRP-alpha; SRPR; SRPRA
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Gene Symbols: SRPRA
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Molecular weight:
69,811 Da
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Basal Isoelectric point:
9.07
Predict pI for various phosphorylation states
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