REEP4 Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes. Belongs to the DP1 family. Expressed in circumvallate papillae and testis. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of human Ortholog: 8p21.3
Cellular Component:  endoplasmic reticulum; endoplasmic reticulum membrane; integral component of membrane; microtubule
Molecular Function:  microtubule binding
Biological Process:  cell division; mitotic nuclear envelope reassembly; nuclear envelope organization
Reference #:  Q9H6H4 (UniProtKB)
Alt. Names/Synonyms: C8orf20; FLJ22246; FLJ22277; PP432; receptor accessory protein 4; receptor expression enhancing protein 4; Receptor expression-enhancing protein 4; REEP4; Yip2c
Gene Symbols: REEP4
Molecular weight: 29,395 Da
Basal Isoelectric point: 9.74  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB