Nedd4-BP2 Has 5'-polynucleotide kinase and nicking endonuclease activity. May play a role in DNA repair or recombination. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 3.-.-.-; Hydrolase; Kinase, other
Chromosomal Location of Human Ortholog: 4p14
Cellular Component:  cytosol
Molecular Function:  ATP binding; ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; endonuclease activity; protein binding
Biological Process:  nucleic acid phosphodiester bond hydrolysis; phosphorylation
Reference #:  Q86UW6 (UniProtKB)
Alt. Names/Synonyms: B3BP; BCL-3 binding protein; BCL-3-binding protein; FLJ10680; KIAA1413; N4BP2; NEDD4 binding protein 2; NEDD4-binding protein 2
Gene Symbols: N4BP2
Molecular weight: 198,801 Da
Basal Isoelectric point: 5.11  Predict pI for various phosphorylation states
Select Structure to View Below

Nedd4-BP2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  CCLE  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB