plakophilin 4 Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques. Belongs to the beta-catenin family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion
Chromosomal Location of Human Ortholog: 2|2 C1.1
Cellular Component:  cell junction; cell-cell adherens junction; cell-cell junction; cytoplasm; cytoplasmic side of plasma membrane; cytoskeleton; desmosome; membrane; midbody; mitotic spindle; nucleus; perinuclear region of cytoplasm; plasma membrane; postsynaptic density; spindle midzone; spindle pole
Molecular Function:  cadherin binding
Biological Process:  cell adhesion; cell-cell adhesion; cell-cell junction assembly; positive regulation of cytokinesis; positive regulation of GTPase activity
Reference #:  Q68FH0 (UniProtKB)
Alt. Names/Synonyms: 5031422I09Rik; 9430019K17Rik; Armadillo-related protein; Armrp; MGC100358; MGC105166; OTTMUSP00000013629; p007; p0071; Pkp4; plakophilin 4; Plakophilin-4; RP23-311G5.1
Gene Symbols: Pkp4
Molecular weight: 131,551 Da
Basal Isoelectric point: 9.07  Predict pI for various phosphorylation states
Select Structure to View Below

plakophilin 4

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein