calponin 3 Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family. Expressed in both non-smooth muscle tissues as well as smooth muscle tissues. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 3|3 G1
Cellular Component:  actin cytoskeleton; cytosol; dendrite; dendritic spine; neuronal cell body; postsynaptic density
Molecular Function:  actin binding; calmodulin binding; microtubule binding; protein binding
Biological Process:  actomyosin structure organization; negative regulation of ATPase activity
Reference #:  Q9DAW9 (UniProtKB)
Alt. Names/Synonyms: 1600014M03Rik; C85854; Calpo3; calponin 3; calponin 3, acidic; Calponin, acidic isoform; Calponin-3; Cnn3
Gene Symbols: Cnn3
Molecular weight: 36,429 Da
Basal Isoelectric point: 5.46  Predict pI for various phosphorylation states
Select Structure to View Below

calponin 3

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene