SPRY3 May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. Belongs to the sprouty family. Widely expressed; particularly in the fetal tissues. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of human Ortholog: Xq28 and Yq12
Cellular Component:  membrane
Biological Process:  axon development; multicellular organism development
Reference #:  O43610 (UniProtKB)
Alt. Names/Synonyms: antagonist of FGF signaling; HSPRY3; Protein sprouty homolog 3; sprouty homolog 3; sprouty homolog 3 (Drosophila); sprouty RTK signaling antagonist 3; Spry-3; SPRY3; SPY3
Gene Symbols: SPRY3
Molecular weight: 31,222 Da
Basal Isoelectric point: 7.4  Predict pI for various phosphorylation states
CST Pathways:  ErbB/HER Signaling  |  Growth And Differentiation Control by MAPKs
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SPRY3

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene