GTL3 Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation. Belongs to the CFAP20 family. Note: This description may include information from UniProtKB.
Protein type: Spliceosome
Chromosomal Location of human Ortholog: 16q21
Cellular Component:  centriole; ciliary basal body; cilium; microtubule; nucleus
Molecular Function:  protein binding
Biological Process:  cilium assembly; multicellular organism development; positive regulation of cell motility; positive regulation of feeding behavior; protein polyglutamylation; regulation of cilium beat frequency involved in ciliary motility
Reference #:  Q9Y6A4 (UniProtKB)
Alt. Names/Synonyms: Basal body up-regulated protein 22; BUG22; C16orf80; CFA20; CFAP20; cilia and flagella associated protein 20; Cilia- and flagella-associated protein 20; EVORF; flagellar associated protein 20 homolog; fSAP23; functional spliceosome-associated protein 23; gene trap locus 3; GTL3; Transcription factor IIB; UPF0468 protein C16orf80
Gene Symbols: CFAP20
Molecular weight: 22,774 Da
Basal Isoelectric point: 9.78  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene