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ACP1
Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity. Belongs to the low molecular weight phosphotyrosine protein phosphatase family. T-lymphocytes express only isoform 2. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cofactor and Vitamin Metabolism - riboflavin; EC 3.1.3.2; EC 3.1.3.48; Motility/polarity/chemotaxis; Phosphatase (non-protein); Protein phosphatase, tyrosine (non-receptor) |
| Chromosomal Location of human Ortholog: 2p25.3 |
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Cellular Component:
cytoplasm; cytoplasmic side of plasma membrane; cytosol; sarcolemma
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Molecular Function:
acid phosphatase activity; non-membrane spanning protein tyrosine phosphatase activity; protein binding; protein tyrosine phosphatase activity
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Biological Process:
protein dephosphorylation
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Reference #:
P24666
(UniProtKB)
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Alt. Names/Synonyms: acid phosphatase 1; acid phosphatase 1, soluble; acid phosphatase of erythrocyte; ACP1; Adipocyte acid phosphatase; cytoplasmic phosphotyrosyl protein phosphatase; HAAP; LMW-PTP; LMW-PTPase; LMWPTP; Low molecular weight cytosolic acid phosphatase; Low molecular weight phosphotyrosine protein phosphatase; MGC111030; MGC3499; PPAC; protein tyrosine phosphatase; Red cell acid phosphatase 1; testicular secretory protein Li 37
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Gene Symbols: ACP1
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Molecular weight:
18,042 Da
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Basal Isoelectric point:
6.29
Predict pI for various phosphorylation states
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