PTAFR Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Expressed in the placenta, lung, left and right heart ventricles, heart atrium, leukocytes and differentiated HL-60 granulocytes. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Receptor, GPCR
Cellular Component: 
Reference #:  Q62035 (UniProtKB)
Alt. Names/Synonyms: PAF-R; PAFr; Platelet-activating factor receptor; Ptafr
Gene Symbols: Ptafr
Molecular weight: 39,148 Da
Basal Isoelectric point: 9.04  Predict pI for various phosphorylation states
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PTAFR

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Ensembl Gene