prolactin Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family. Note: This description may include information from UniProtKB.
Protein type: Cytokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of mouse Ortholog: 13 A3.1|13 12.25 cM
Cellular Component:  extracellular region; extracellular space; secretory granule
Molecular Function:  hormone activity; prolactin receptor binding
Biological Process:  cell population proliferation; epithelial cell proliferation; female pregnancy; lactation; mammary gland development; maternal behavior; negative regulation of endothelial cell proliferation; positive regulation of cell population proliferation; positive regulation of epithelial cell proliferation; positive regulation of lactation; positive regulation of miRNA transcription; positive regulation of receptor signaling pathway via JAK-STAT; regulation of ossification; regulation of receptor signaling pathway via JAK-STAT; response to nutrient levels
Reference #:  P06879 (UniProtKB)
Alt. Names/Synonyms: AV290867; Gha1; growth hormone a1; PRL; Prl1a1; Prolactin
Gene Symbols: Prl
Molecular weight: 25,496 Da
Basal Isoelectric point: 5.28  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene