prolactin
Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family. Note: This description may include information from UniProtKB.
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Protein type: Cytokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide |
Chromosomal Location of human Ortholog: 6p22.3 |
Cellular Component:
endosome lumen; extracellular region; extracellular space
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Molecular Function:
hormone activity; prolactin receptor binding; protein binding
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Biological Process:
cell surface receptor signaling pathway; female pregnancy; lactation; mammary gland development; negative regulation of angiogenesis; negative regulation of endothelial cell proliferation; positive regulation of cell population proliferation; positive regulation of lactation; positive regulation of miRNA transcription; positive regulation of receptor signaling pathway via JAK-STAT; response to nutrient levels
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Reference #:
P01236
(UniProtKB)
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Alt. Names/Synonyms: decidual prolactin; GHA1; growth hormone A1; PRL; Prolactin
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Gene Symbols: PRL
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Molecular weight:
25,876 Da
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Basal Isoelectric point:
6.5
Predict pI for various phosphorylation states
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