prolactin Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family. Note: This description may include information from UniProtKB.
Protein type: Cytokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 6p22.3
Cellular Component:  endosome lumen; extracellular region
Molecular Function:  protein binding
Biological Process:  cell surface receptor signaling pathway; cellular protein metabolic process; JAK-STAT cascade involved in growth hormone signaling pathway; lactation; negative regulation of angiogenesis; negative regulation of endothelial cell proliferation; positive regulation of JAK-STAT cascade; positive regulation of pri-miRNA transcription by RNA polymerase II; regulation of multicellular organism growth; regulation of signaling receptor activity
Reference #:  P01236 (UniProtKB)
Alt. Names/Synonyms: decidual prolactin; GHA1; growth hormone A1; PRL; Prolactin
Gene Symbols: PRL
Molecular weight: 25,876 Da
Basal Isoelectric point: 6.5  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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