LXN Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation. Belongs to the protease inhibitor I47 (latexin) family. Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain. Note: This description may include information from UniProtKB.
Protein type: Inhibitor
Chromosomal Location of Human Ortholog: 3q25.32
Cellular Component:  cytoplasm
Molecular Function:  heparin binding; metalloendopeptidase inhibitor activity; protein binding
Biological Process:  detection of temperature stimulus involved in sensory perception of pain; inflammatory response; negative regulation of endopeptidase activity
Reference #:  Q9BS40 (UniProtKB)
Alt. Names/Synonyms: ECI; Endogenous carboxypeptidase inhibitor; Latexin; LXN; MUM; Protein MUM; TCI; Tissue carboxypeptidase inhibitor
Gene Symbols: LXN
Molecular weight: 25,750 Da
Basal Isoelectric point: 5.54  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene