PRM1 Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. Belongs to the protamine P1 family. Testis. Note: This description may include information from UniProtKB.
Protein type: Cancer Testis Antigen (CTA); DNA-binding
Chromosomal Location of Human Ortholog: 16 A1|16 5.87 cM
Cellular Component:  chromosome; nucleosome; nucleus
Molecular Function:  DNA binding
Biological Process:  cell differentiation; chromosome condensation; multicellular organism development; nucleus organization; spermatid development; spermatogenesis
Reference #:  P02319 (UniProtKB)
Alt. Names/Synonyms: CT94.1; Cysteine-rich protamine; HSP1; OTTMUSP00000031138; Prm-1; Prm1; protamine 1; Sperm protamine P1; sperm protamine-P1
Gene Symbols: Prm1
Molecular weight: 6,958 Da
Basal Isoelectric point: 12.07  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene