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PRM2
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. Belongs to the protamine P2 family. Testis. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cancer Testis Antigen (CTA); DNA-binding |
| Chromosomal Location of mouse Ortholog: 16 A1|16 5.84 cM |
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Cellular Component:
chromosome; cytoplasm; male germ cell nucleus; nucleosome; nucleus
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Molecular Function:
cadmium ion binding; DNA binding; zinc ion binding
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Biological Process:
cell differentiation; chromosome condensation; chromosome organization; multicellular organism development; nucleus organization; spermatid development; spermatogenesis
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Reference #:
P07978
(UniProtKB)
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Alt. Names/Synonyms: AI528784; CT94.2; PP2-A; PP2-B; PP2-C; PP2-D; Prm; Prm-2; Prm2; protamine 2; Protamine MP2; Protamine-2; Sperm histone P2; Sperm protamine P2; sperm protamine-P2
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Gene Symbols: Prm2
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Molecular weight:
13,638 Da
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Basal Isoelectric point:
12.05
Predict pI for various phosphorylation states
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