TFPT Appears to promote apoptosis in a p53/TP53-independent manner. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Oncoprotein
Chromosomal Location of Human Ortholog: 7|7 A1
Cellular Component:  cytoplasm; Ino80 complex; nuclear membrane; nucleoplasm; nucleus
Molecular Function:  DNA binding; protein heterodimerization activity; protein kinase binding
Biological Process:  apoptotic process; apoptotic signaling pathway; cellular response to DNA damage stimulus; DNA recombination; DNA repair; positive regulation of apoptotic process
Reference #:  Q3U1J1 (UniProtKB)
Alt. Names/Synonyms: 2400004F01Rik; AI450389; Amida; FB1; OTTMUSP00000027358; Protein amida; Protein FB1; TCF3 (E2A) fusion partner; TCF3 fusion partner homolog; Tfpt
Gene Symbols: Tfpt
Molecular weight: 28,954 Da
Basal Isoelectric point: 4.85  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene