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PKIG
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family. Ubiquitous. Note: This description may include information from UniProtKB.
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| Protein type: Inhibitor; Protein kinase, regulatory subunit |
| Chromosomal Location of human Ortholog: 20q13.12 |
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Cellular Component:
cytoplasm; nucleus
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Molecular Function:
cAMP-dependent protein kinase inhibitor activity; protein binding
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Biological Process:
negative regulation of cAMP-dependent protein kinase activity; negative regulation of protein import into nucleus; negative regulation of transcription by RNA polymerase II
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Reference #:
Q9Y2B9
(UniProtKB)
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Alt. Names/Synonyms: cAMP-dependent protein kinase inhibitor gamma; IPKG; MGC126458; MGC126459; PKI-gamma; PKIG; protein kinase (cAMP-dependent, catalytic) inhibitor gamma
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Gene Symbols: PKIG
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Molecular weight:
7,910 Da
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Basal Isoelectric point:
4.11
Predict pI for various phosphorylation states
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