FPGT Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate. Functions as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. Expressed in many tissues. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - fructose and mannose; EC 2.7.7.30; Transferase
Chromosomal Location of Human Ortholog: 1p31.1
Cellular Component:  cytoplasm; cytosol
Molecular Function:  catalytic activity; fucose-1-phosphate guanylyltransferase activity; GTP binding
Biological Process:  fucose metabolic process
Reference #:  O14772 (UniProtKB)
Alt. Names/Synonyms: FPGT; fucose-1-phosphate guanyltransferase; Fucose-1-phosphate guanylyltransferase; GDP-beta-L-fucose pyrophosphorylase; GDP-L-fucose diphosphorylase; GDP-L-fucose pyrophosphorylase; GFPP
Gene Symbols: FPGT
Molecular weight: 68,010 Da
Basal Isoelectric point: 6.45  Predict pI for various phosphorylation states
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FPGT

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene