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CRIPT
Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. Belongs to the CRIPT family. Note: This description may include information from UniProtKB.
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| Protein type: Adaptor/scaffold; Microtubule-binding |
| Chromosomal Location of human Ortholog: 2p21 |
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Cellular Component:
cytoplasm; dendrite; dendritic shaft; dendritic spine; glutamatergic synapse; neuronal cell body; postsynaptic density; postsynaptic density, intracellular component; spliceosomal complex
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Molecular Function:
microtubule binding; PDZ domain binding; protein binding; protein-containing complex binding; scaffold protein binding
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Biological Process:
cytoplasmic microtubule organization; establishment of protein localization; mRNA processing; protein localization to microtubule; regulation of postsynaptic density assembly; regulation of postsynaptic density protein 95 clustering; RNA splicing
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Disease: Short Stature With Microcephaly And Distinctive Facies
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Reference #:
Q9P021
(UniProtKB)
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Alt. Names/Synonyms: CRIPT; CXXC repeat containing interactor of PDZ3 domain; Cysteine-rich interactor of PDZ three; Cysteine-rich interactor of PDZ3; Cysteine-rich PDZ-binding protein; HSPC139; postsynaptic protein CRIPT; SSMDF
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Gene Symbols: CRIPT
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Molecular weight:
11,216 Da
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Basal Isoelectric point:
9.57
Predict pI for various phosphorylation states
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