CA6
Reversible hydration of carbon dioxide. Its role in saliva is unknown. Belongs to the alpha-carbonic anhydrase family. Major constituent of saliva. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: EC 4.2.1.1; Energy Metabolism - nitrogen; Lyase; Secreted; Secreted, signal peptide |
Chromosomal Location of human Ortholog: 1p36.23 |
Cellular Component:
cytosol; extracellular region; extracellular space
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Molecular Function:
carbonate dehydratase activity; zinc ion binding
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Biological Process:
detection of chemical stimulus involved in sensory perception of bitter taste; one-carbon metabolic process
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Reference #:
P23280
(UniProtKB)
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Alt. Names/Synonyms: CA-VI; CA6; CAH6; Carbonate dehydratase VI; Carbonic anhydrase 6; Carbonic anhydrase VI; carbonic anhydrase VI nirs variant 2; GUSTIN; MGC21256; Salivary carbonic anhydrase; Secreted carbonic anhydrase
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Gene Symbols: CA6
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Molecular weight:
35,367 Da
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Basal Isoelectric point:
6.51
Predict pI for various phosphorylation states
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