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G-alpha(z)
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Belongs to the G-alpha family. G(i/o/t/z) subfamily. Note: This description may include information from UniProtKB.
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| Protein type: Endoplasmic reticulum; G protein, heterotrimeric; G protein, heterotrimeric alpha G((i/o/t/z)); Nuclear envelope |
| Chromosomal Location of mouse Ortholog: 10 C1|10 38.48 cM |
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Cellular Component:
cell body; cytosol; dendrite; heterotrimeric G-protein complex; membrane; plasma membrane
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Molecular Function:
G protein-coupled receptor binding; G protein-coupled serotonin receptor binding; G-protein beta/gamma-subunit complex binding; GTP binding; GTPase activity; guanyl nucleotide binding; metal ion binding; nucleotide binding
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Biological Process:
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway; G protein-coupled serotonin receptor signaling pathway; signal transduction
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Reference #:
O70443
(UniProtKB)
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Alt. Names/Synonyms: AI847979; G(x) alpha chain; G-alpha(z); Gnaz; guanine nucleotide binding protein, alpha z subunit; Guanine nucleotide-binding protein G(z) subunit alpha; Gz; Gz-alpha
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Gene Symbols: Gnaz
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Molecular weight:
40,850 Da
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Basal Isoelectric point:
7.53
Predict pI for various phosphorylation states
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CST Pathways:
Microtubule Dynamics
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Phospholipase Signaling
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PI3K/Akt Signaling
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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