EPB41L2 Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase. Widely expressed. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 6q23.1-q23.2
Cellular Component:  cell cortex region; cell junction; cytosol; nucleoplasm; nucleus; plasma membrane; spectrin
Molecular Function:  actin binding; PH domain binding; protein binding; spectrin binding; structural molecule activity
Biological Process:  cell cycle; cell division; cortical actin cytoskeleton organization; positive regulation of protein localization to cell cortex
Reference #:  O43491 (UniProtKB)
Alt. Names/Synonyms: 4.1-G; 4.1G; Band 4.1-like protein 2; DKFZp781D1972; DKFZp781H1755; E41L2; EPB41L2; erythrocyte membrane protein band 4.1 like 2; erythrocyte membrane protein band 4.1 like-protein 2; erythrocyte membrane protein band 4.1-like 2; Generally expressed protein 4.1
Gene Symbols: EPB41L2
Molecular weight: 112,588 Da
Basal Isoelectric point: 5.34  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene