PRM1 Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. Belongs to the protamine P1 family. Testis. Note: This description may include information from UniProtKB.
Protein type: Cancer Testis Antigen (CTA); DNA-binding
Chromosomal Location of human Ortholog: 16p13.13
Cellular Component:  cytosol; nucleoplasm; nucleosome
Molecular Function:  DNA binding; protein binding
Biological Process:  chromosome condensation; chromosome organization; sperm DNA condensation; spermatogenesis
Reference #:  P04553 (UniProtKB)
Alt. Names/Synonyms: cancer/testis antigen family 94, member 1; CT94.1; Cysteine-rich protamine; HSP1; OTTHUMP00000115605; P1; PRM1; protamine 1; Sperm protamine P1; testicular tissue protein Li 91; testis specific protamine 1
Gene Symbols: PRM1
Molecular weight: 6,823 Da
Basal Isoelectric point: 12.08  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein