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PRM1
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. Belongs to the protamine P1 family. Testis. Note: This description may include information from UniProtKB.
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| Protein type: Cancer Testis Antigen (CTA); DNA-binding |
| Chromosomal Location of human Ortholog: 16p13.13 |
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Cellular Component:
cytosol; nucleoplasm; nucleosome
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Molecular Function:
DNA binding; protein binding
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Biological Process:
chromosome condensation; chromosome organization; sperm DNA condensation; spermatogenesis
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Reference #:
P04553
(UniProtKB)
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Alt. Names/Synonyms: cancer/testis antigen family 94, member 1; CT94.1; Cysteine-rich protamine; HSP1; OTTHUMP00000115605; P1; PRM1; protamine 1; Sperm protamine P1; testicular tissue protein Li 91; testis specific protamine 1
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Gene Symbols: PRM1
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Molecular weight:
6,823 Da
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Basal Isoelectric point:
12.08
Predict pI for various phosphorylation states
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