gastrin Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. Belongs to the gastrin/cholecystokinin family. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q21.2
Cellular Component:  extracellular region
Molecular Function:  protein binding
Biological Process:  G protein-coupled receptor signaling pathway; regulation of signaling receptor activity; signal transduction
Reference #:  P01350 (UniProtKB)
Alt. Names/Synonyms: Big gastrin; G14; G17; G34; G52; G6; GAS; GAST; Gastrin; Gastrin component I; Gastrin component II; Gastrin component III; Gastrin-14; Gastrin-17; Gastrin-34; Gastrin-52; Gastrin-6; Gastrin-71; preprogastrin
Gene Symbols: GAST
Molecular weight: 11,394 Da
Basal Isoelectric point: 5.08  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene