GDAP1 iso2
Regulates the mitochondrial network by promoting mitochondrial fission. Belongs to the GST superfamily. Highly expressed in whole brain and spinal cord. Predominant expression in central tissues of the nervous system not only in neurons but also in Schwann cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Membrane protein, multi-pass |
Chromosomal Location of human Ortholog: 8q21.11 |
Cellular Component:
cytosol; mitochondrial outer membrane; mitochondrion; peroxisomal membrane
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Molecular Function:
protein binding
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Biological Process:
cellular response to vitamin D; mitochondrial fission; mitochondrial fusion; protein targeting to mitochondrion; response to retinoic acid
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Reference #:
Q8TB36-2
(UniProtKB)
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Alt. Names/Synonyms: Charcot-Marie-Tooth neuropathy 4A; CMT4; CMT4A; CMTRIA; ganglioside induced differentiation associated protein 1; Ganglioside-induced differentiation-associated protein 1; GDAP1; GDAP1 iso2
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Gene Symbols: GDAP1
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Molecular weight:
33,480 Da
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Basal Isoelectric point:
9.07
Predict pI for various phosphorylation states
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