TAS2R1 Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family. Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Note: This description may include information from UniProtKB.
Protein type: GPCR, T2R family; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 5p15.31
Cellular Component:  integral component of membrane; plasma membrane
Molecular Function:  bitter taste receptor activity; G protein-coupled receptor activity; taste receptor activity
Biological Process:  detection of chemical stimulus involved in sensory perception of bitter taste; G protein-coupled receptor signaling pathway
Reference #:  Q9NYW7 (UniProtKB)
Alt. Names/Synonyms: MGC126778; MGC126780; T2R1; TA2R1; TAS2R1; taste 2 receptor member 1; Taste receptor family B member 7; Taste receptor type 2 member 1; taste receptor, family B, member 7; taste receptor, type 2, member 1; TRB7
Gene Symbols: TAS2R1
Molecular weight: 34,333 Da
Basal Isoelectric point: 9.87  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB