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TMEM170A
Acts as a regulator of endoplasmic reticulum (ER) and nuclear envelope (NE) morphogenesis. Affects the ratio between tubular ER and ER sheets by promoting sheet formation at the expense of tubules. Influences NE expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins. Belongs to the TMEM170 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral; Membrane protein, multi-pass |
| Chromosomal Location of human Ortholog: 16q23.1 |
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Cellular Component:
endoplasmic reticulum membrane; nuclear envelope
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Molecular Function:
protein binding
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Biological Process:
endoplasmic reticulum tubular network organization; nuclear envelope organization; nuclear pore complex assembly
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Reference #:
Q8WVE7
(UniProtKB)
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Alt. Names/Synonyms: FLJ37611; T170A; TMEM170; TMEM170A; transmembrane protein 170; Transmembrane protein 170A
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Gene Symbols: TMEM170A
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Molecular weight:
15,250 Da
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Basal Isoelectric point:
9.3
Predict pI for various phosphorylation states
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