FABP4 Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Note: This description may include information from UniProtKB.
Protein type: Lipid-binding
Chromosomal Location of Human Ortholog: 8q21.13
Cellular Component:  cytoplasm; cytosol; lipid droplet; nucleus
Molecular Function:  fatty acid binding; hormone receptor binding; long-chain fatty acid binding; long-chain fatty acid transporter activity
Biological Process:  brown fat cell differentiation; cellular response to lithium ion; cellular response to tumor necrosis factor; cholesterol homeostasis; cytokine production; long-chain fatty acid transport; negative regulation of protein kinase activity; negative regulation of transcription, DNA-templated; positive regulation of cold-induced thermogenesis; positive regulation of inflammatory response; response to bacterium; triglyceride catabolic process; white fat cell differentiation
Reference #:  P15090 (UniProtKB)
Alt. Names/Synonyms: A-FABP; Adipocyte lipid-binding protein; Adipocyte-type fatty acid-binding protein; AFABP; ALBP; aP2; FABP4; fatty acid binding protein 4, adipocyte; Fatty acid-binding protein 4; Fatty acid-binding protein, adipocyte
Gene Symbols: FABP4
Molecular weight: 14,719 Da
Basal Isoelectric point: 6.59  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below

FABP4

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene