stomatin
Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity. Belongs to the band 7/mec-2 family. Detected in erythrocytes (at protein level). Widely expressed. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Adaptor/scaffold; Membrane protein, integral; Motility/polarity/chemotaxis |
Chromosomal Location of mouse Ortholog: 2 B|2 23.53 cM |
Cellular Component:
cytoplasm; cytoplasmic vesicle; cytoskeleton; endoplasmic reticulum; membrane; membrane raft; mitochondrion; perinuclear region of cytoplasm; plasma membrane
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Molecular Function:
identical protein binding; protein binding; protein homodimerization activity; RNA polymerase binding
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Biological Process:
positive regulation by host of viral genome replication; positive regulation of protein targeting to membrane; positive regulation of viral process; regulation of acid-sensing ion channel activity; regulation of monoatomic ion transmembrane transport
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Reference #:
P54116
(UniProtKB)
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Alt. Names/Synonyms: Epb7.; Epb7.2; Epb72; Erythrocyte band 7 integral membrane protein; erythrocyte protein band 7.2; OTTMUSP00000013019; Protein 7.2b; sto; Stom; Stomatin
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Gene Symbols: Stom
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Molecular weight:
31,375 Da
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Basal Isoelectric point:
6.46
Predict pI for various phosphorylation states
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