Rab4 Protein transport. Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling. Belongs to the small GTPase superfamily. Rab family. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab
Chromosomal Location of human Ortholog: 1q42.13
Cellular Component:  cytoplasmic vesicle membrane; early endosome membrane; extracellular exosome; insulin-responsive compartment; perinuclear region of cytoplasm; postsynaptic recycling endosome; recycling endosome membrane; vesicle
Molecular Function:  G protein activity; GDP binding; GTP binding; GTPase activity; protein binding
Biological Process:  antigen processing and presentation; protein transport; Rab protein signal transduction; regulation of endocytosis; vesicle-mediated transport
Reference #:  P20338 (UniProtKB)
Alt. Names/Synonyms: HRES-1; HRES-1/RAB4; HRES1; HTLV-1 related endogenous sequence; Oncogene RAB4; RAB4; RAB4, member RAS oncogene family; RAB4A; RAB4A, member RAS oncogene family; Ras-related protein Rab-4A
Gene Symbols: RAB4A
Molecular weight: 24,390 Da
Basal Isoelectric point: 5.82  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Rab4

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein