TP1 Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. Belongs to the nuclear transition protein 1 family. Expressed by spermatids (at protein level). Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Cellular Component: 
Reference #:  P22613 (UniProtKB)
Alt. Names/Synonyms: Protein T; Spermatid nuclear transition protein 1; STP-1; STP1; TNP1; TP-1; TP1; transition protein 1
Gene Symbols: TNP1
Molecular weight: 6,344 Da
Basal Isoelectric point: 11.94  Predict pI for various phosphorylation states
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TP1

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept