HLAB iso9 Involved in the presentation of foreign antigens to the immune system. Belongs to the MHC class I family. Note: This description may include information from UniProtKB.
Protein type: Immunoglobulin superfamily; Membrane protein, integral
Chromosomal Location of human Ortholog: 6p21.33
Cellular Component:  cell surface; early endosome membrane; endoplasmic reticulum; ER to Golgi transport vesicle membrane; external side of plasma membrane; extracellular space; Golgi apparatus; Golgi membrane; lumenal side of endoplasmic reticulum membrane; membrane; MHC class I protein complex; phagocytic vesicle membrane; plasma membrane; recycling endosome membrane; secretory granule membrane
Molecular Function:  peptide antigen binding; protein binding; protein-folding chaperone binding; signaling receptor binding; TAP binding
Biological Process:  adaptive immune response; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib; defense response; detection of bacterium; immune response; innate immune response; positive regulation of T cell mediated cytotoxicity; protection from natural killer cell mediated cytotoxicity; regulation of dendritic cell differentiation; regulation of interleukin-12 production; regulation of interleukin-6 production; regulation of T cell anergy
Disease: Severe Cutaneous Adverse Reaction, Susceptibility To; Spondyloarthropathy, Susceptibility To, 1
Reference #:  P01889_VAR_C349S (UniProtKB)
Alt. Names/Synonyms: AS; B-4901; HLA class I antigen HLA-B; HLA class I histocompatibility antigen, B alpha chain; HLA-B; HLAB; HLAB iso9; Human leukocyte antigen B; leukocyte antigen class I-B; major histocompatibility complex, class I, B; MHC class 1 antigen; MHC class I antigen HLA-B alpha chain; MHC class I antigen HLA-B heavy chain; MHC class I antigen SHCHA; MHC class I molecule; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein
Gene Symbols: HLA-B
Molecular weight: 40,444 Da
Basal Isoelectric point: 5.57  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below

HLAB iso9

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene