Myf-6
Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. Skeletal muscle. Note: This description may include information from UniProtKB.
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Protein type: DNA-binding; Transcription factor |
Chromosomal Location of rat Ortholog: 7q21 |
Cellular Component:
cytosol; membrane; mitotic spindle; nucleoplasm; nucleus
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Molecular Function:
DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; protein dimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific double-stranded DNA binding
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Biological Process:
cell differentiation; muscle organ development; muscle tissue morphogenesis; negative regulation of DNA-templated transcription; positive regulation of DNA-templated transcription; positive regulation of myoblast differentiation; positive regulation of skeletal muscle fiber development; regulation of DNA-templated transcription; regulation of transcription by RNA polymerase II; skeletal muscle cell differentiation; skeletal muscle tissue development; skeletal muscle tissue regeneration; somitogenesis
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Reference #:
P19335
(UniProtKB)
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Alt. Names/Synonyms: Mrf4; MRF4AA; Muscle-specific regulatory factor 4; Myf-6; Myf6; Myogenic factor 6; Myogenic factor 6 (herculin)
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Gene Symbols: Myf6
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Molecular weight:
26,987 Da
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Basal Isoelectric point:
5.71
Predict pI for various phosphorylation states
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