HNF4G Transcription factor. Has a lower transcription activation potential than HNF4-alpha. Belongs to the nuclear hormone receptor family. NR2 subfamily. Expressed in pancreas, kidney, small intestine and testis. Weakly expressed in colon. Not expressed in liver, skeletal muscle, lung, placenta, brain, heart, peripheral blood, ovary, prostate, thymus and spleen. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Nuclear receptor
Chromosomal Location of human Ortholog: 8q21.13
Cellular Component:  chromatin; cytosol; intercellular bridge; mitotic spindle; nucleoplasm
Molecular Function:  DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; nuclear receptor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; zinc ion binding
Biological Process:  anatomical structure development; cell differentiation; intracellular receptor signaling pathway; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II
Reference #:  Q14541 (UniProtKB)
Alt. Names/Synonyms: hepatocyte nuclear factor 4 gamma; hepatocyte nuclear factor 4, gamma; Hepatocyte nuclear factor 4-gamma; HNF-4-gamma; HNF4G; NR2A2; NR2A3; Nuclear receptor subfamily 2 group A member 2
Gene Symbols: HNF4G
Molecular weight: 45,877 Da
Basal Isoelectric point: 8.68  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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HNF4G

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  NURSA