ERM Binds to DNA sequences containing the consensus nucleotide core sequence 5'-GGAA.-3'. Belongs to the ETS family. Ubiquitous. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of mouse Ortholog: 16|16 B1
Cellular Component:  nucleoplasm; nucleus
Molecular Function:  DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding; sequence-specific DNA binding; transcription regulatory region DNA binding
Biological Process:  cell differentiation; cellular response to oxidative stress; locomotory behavior; male germ-line stem cell asymmetric division; neuromuscular synaptic transmission; positive regulation of glial cell proliferation; positive regulation of neuron differentiation; positive regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated; regulation of branching involved in mammary gland duct morphogenesis; regulation of synapse organization; regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; skeletal muscle acetylcholine-gated channel clustering
Reference #:  Q9CXC9 (UniProtKB)
Alt. Names/Synonyms: 1110005E01Rik; 8430401F14Rik; ERM; ETS translocation variant 5; ets variant 5; ets variant gene 5; Etv5
Gene Symbols: Etv5
Molecular weight: 57,712 Da
Basal Isoelectric point: 5.39  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene