ERM Binds to DNA sequences containing the consensus nucleotide core sequence 5'-GGAA.-3'. Belongs to the ETS family. Ubiquitous. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 3q27.2
Cellular Component:  nucleoplasm; nucleus; plasma membrane
Molecular Function:  DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding; RNA polymerase II regulatory region sequence-specific DNA binding; transcription regulatory region DNA binding
Biological Process:  cellular response to oxidative stress; locomotory behavior; male germ-line stem cell asymmetric division; neuromuscular synaptic transmission; positive regulation of glial cell proliferation; positive regulation of neuron differentiation; positive regulation of transcription by RNA polymerase II; regulation of branching involved in mammary gland duct morphogenesis; regulation of synapse organization; skeletal muscle acetylcholine-gated channel clustering
Reference #:  P41161 (UniProtKB)
Alt. Names/Synonyms: ERM; ETS translocation variant 5; ets variant 5; ETS variant transcription factor 5; ets-related molecule; Ets-related protein ERM; ETV5
Gene Symbols: ETV5
Molecular weight: 57,838 Da
Basal Isoelectric point: 5.43  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene