ADORA2A Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Cellular Component:  plasma membrane; postsynapse
Molecular Function:  enzyme binding; identical protein binding; lipid binding
Biological Process:  apoptotic signaling pathway; eating behavior; inhibitory postsynaptic potential; locomotory behavior; negative regulation of alpha-beta T cell activation; negative regulation of inflammatory response; positive regulation of apoptotic signaling pathway; positive regulation of synaptic transmission, GABAergic; response to amphetamine; response to inorganic substance; response to purine-containing compound; synaptic transmission, dopaminergic
Reference #:  P11617 (UniProtKB)
Alt. Names/Synonyms: A2aR; AA2AR; adenosine A2a receptor; Adenosine receptor A2a; ADORA2A; RDC8
Gene Symbols: ADORA2A
Molecular weight: 45,061 Da
Basal Isoelectric point: 8.63  Predict pI for various phosphorylation states
Select Structure to View Below

ADORA2A
Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene