TACSTD2 May function as a growth factor receptor. Belongs to the EPCAM family. Placenta, pancreatic carcinoma cell lines. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of human Ortholog: 1p32.1
Cellular Component:  basal plasma membrane; cytosol; integral component of membrane; lateral plasma membrane; membrane
Molecular Function:  protein binding
Biological Process:  cell-cell adhesion; negative regulation of branching involved in ureteric bud morphogenesis; negative regulation of cell motility; negative regulation of epithelial cell migration; negative regulation of ruffle assembly; negative regulation of stress fiber assembly; negative regulation of substrate adhesion-dependent cell spreading; regulation of epithelial cell proliferation; response to stimulus; ureteric bud morphogenesis; visual perception
Disease: Corneal Dystrophy, Gelatinous Drop-like
Reference #:  P09758 (UniProtKB)
Alt. Names/Synonyms: 40kD glycoprotein, identified by monoclonal antibody GA733; Cell surface glycoprotein Trop-2; cell surface glycoprotein TROP2; EGP-1; EGP1; epithelial glycoprotein-1; GA733-1; GA7331; gastrointestinal tumor-associated antigen GA7331; GP50; M1S1; Membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; Pancreatic carcinoma marker protein GA733-1; pancreatic carcinoma marker protein GA7331; TACD2; TACSTD2; TROP2; trophoblast cell surface antigen 2; truncated TACSTD2; tumor associated calcium signal transducer 2; Tumor-associated calcium signal transducer 2
Gene Symbols: TACSTD2
Molecular weight: 35,709 Da
Basal Isoelectric point: 9.14  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene