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TACSTD2
May function as a growth factor receptor. Belongs to the EPCAM family. Placenta, pancreatic carcinoma cell lines. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral; Receptor, misc. |
| Chromosomal Location of human Ortholog: 1p32.1 |
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Cellular Component:
basal plasma membrane; cytosol; extracellular space; lateral plasma membrane; membrane; nucleus
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Molecular Function:
protein binding
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Biological Process:
negative regulation of branching involved in ureteric bud morphogenesis; negative regulation of cell motility; negative regulation of epithelial cell migration; negative regulation of ruffle assembly; negative regulation of stress fiber assembly; negative regulation of substrate adhesion-dependent cell spreading; positive regulation of stem cell differentiation; regulation of epithelial cell proliferation; response to stimulus; ureteric bud morphogenesis; visual perception
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Disease: Corneal Dystrophy, Gelatinous Drop-like
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Reference #:
P09758
(UniProtKB)
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Alt. Names/Synonyms: 40kD glycoprotein, identified by monoclonal antibody GA733; Cell surface glycoprotein Trop-2; cell surface glycoprotein TROP2; EGP-1; EGP1; epithelial glycoprotein-1; GA733-1; GA7331; gastrointestinal tumor-associated antigen GA7331; GP50; M1S1; Membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; Pancreatic carcinoma marker protein GA733-1; pancreatic carcinoma marker protein GA7331; TACD2; TACSTD2; TROP2; trophoblast cell surface antigen 2; truncated TACSTD2; tumor associated calcium signal transducer 2; Tumor-associated calcium signal transducer 2
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Gene Symbols: TACSTD2
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Molecular weight:
35,709 Da
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Basal Isoelectric point:
9.14
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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