TMEM176B May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells. Belongs to the TMEM176 family. Expressed in lung and dermal fibroblasts. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of human Ortholog: 7q36.1
Cellular Component:  integral component of membrane; nuclear membrane
Biological Process:  animal organ morphogenesis; cell differentiation; negative regulation of dendritic cell differentiation
Reference #:  Q3YBM2 (UniProtKB)
Alt. Names/Synonyms: FLJ26014; LR8; LR8-like protein; MGC110857; MS4B2; Protein LR8; T176B; TMEM176B; Transmembrane protein 176B
Gene Symbols: TMEM176B
Molecular weight: 29,056 Da
Basal Isoelectric point: 8.81  Predict pI for various phosphorylation states
Select Structure to View Below

TMEM176B

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene