GJB1 One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Beta-type (group I) subfamily. Note: This description may include information from UniProtKB.
Protein type: Channel, misc.; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis
Chromosomal Location of rat Ortholog: Xq22
Cellular Component:  connexin complex; cytoplasm; gap junction; lateral plasma membrane; plasma membrane; protein-containing complex
Molecular Function:  gap junction channel activity; identical protein binding
Biological Process:  cell communication; cell-cell signaling; epididymis development; purine ribonucleotide transport; transmembrane transport
Reference #:  P08033 (UniProtKB)
Alt. Names/Synonyms: connexin 32; Connexin-32; Cx32; CXB1; Cxn-32; GAP junction 28 kDa liver protein; Gap junction beta-1 protein; gap junction membrane channel protein beta 1; gap junction protein, beta 1; Gjb1
Gene Symbols: Gjb1
Molecular weight: 32,004 Da
Basal Isoelectric point: 9.2  Predict pI for various phosphorylation states
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GJB1

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene