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GJB1
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Beta-type (group I) subfamily. Note: This description may include information from UniProtKB.
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| Protein type: Channel, misc.; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis |
| Chromosomal Location of rat Ortholog: Xq22 |
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Cellular Component:
connexin complex; cytoplasm; gap junction; lateral plasma membrane; plasma membrane; protein-containing complex
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Molecular Function:
gap junction channel activity; identical protein binding
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Biological Process:
cell communication; cell-cell signaling; epididymis development; purine ribonucleotide transport; transmembrane transport
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Reference #:
P08033
(UniProtKB)
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Alt. Names/Synonyms: connexin 32; Connexin-32; Cx32; CXB1; Cxn-32; GAP junction 28 kDa liver protein; Gap junction beta-1 protein; gap junction membrane channel protein beta 1; gap junction protein, beta 1; Gjb1
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Gene Symbols: Gjb1
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Molecular weight:
32,004 Da
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Basal Isoelectric point:
9.2
Predict pI for various phosphorylation states
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