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CK1G3
Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: CK1 group; CK1 family; CK1-G subfamily; EC 2.7.11.1; Kinase, protein; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor) |
| Chromosomal Location of mouse Ortholog: 18|18 D1 |
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Cellular Component:
cytoplasm; nucleus; plasma membrane
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Molecular Function:
ATP binding; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity
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Biological Process:
endocytosis; peptidyl-serine phosphorylation; phosphorylation; positive regulation of canonical Wnt signaling pathway; protein autophosphorylation; protein phosphorylation; signal transduction; Wnt signaling pathway
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Reference #:
Q8C4X2
(UniProtKB)
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Alt. Names/Synonyms: 3300002K07Rik; C330049O21Rik; casein kinase 1, gamma 3; casein kinase I; Casein kinase I isoform gamma-3; CK1G3; CKI-gamma 3; Csnk1g3; KC1G3
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Gene Symbols: Csnk1g3
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Molecular weight:
48,938 Da
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Basal Isoelectric point:
9.21
Predict pI for various phosphorylation states
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CST Pathways:
Hedgehog Signaling
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Wnt/ß-Catenin Signaling
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