myogenin Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 1 E4|1 58.18 cM
Cellular Component:  nucleoplasm; nucleus; protein-DNA complex
Molecular Function:  chromatin DNA binding; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; E-box binding; protein binding; protein dimerization activity; proximal promoter sequence-specific DNA binding; RNA polymerase II proximal promoter sequence-specific DNA binding; RNA polymerase II regulatory region sequence-specific DNA binding; sequence-specific DNA binding
Biological Process:  cell cycle; cell differentiation; cellular response to estradiol stimulus; cellular response to growth factor stimulus; cellular response to lithium ion; cellular response to tumor necrosis factor; mRNA transcription by RNA polymerase II; multicellular organism development; muscle organ development; myotube differentiation; negative regulation of cell proliferation; negative regulation of glycolytic process; ossification; positive regulation of cell cycle arrest; positive regulation of muscle atrophy; positive regulation of myoblast differentiation; positive regulation of myoblast fusion; positive regulation of myotube differentiation; positive regulation of oxidative phosphorylation; positive regulation of skeletal muscle fiber development; positive regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated; regulation of myoblast fusion; regulation of skeletal muscle satellite cell proliferation; regulation of transcription, DNA-templated; response to denervation involved in regulation of muscle adaptation; response to electrical stimulus involved in regulation of muscle adaptation; response to muscle activity involved in regulation of muscle adaptation; skeletal muscle cell differentiation; skeletal muscle fiber development; skeletal muscle tissue development; striated muscle atrophy
Reference #:  P12979 (UniProtKB)
Alt. Names/Synonyms: bHLHc3; MYF4; myo; MYOD1-related protein; Myog; Myogenin
Gene Symbols: Myog
Molecular weight: 25,203 Da
Basal Isoelectric point: 5.56  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene