SF3A3 Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes. Belongs to the SF3A3 family. Ubiquitous. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; RNA splicing; RNA-binding; Spliceosome
Chromosomal Location of Human Ortholog: 4|4 D2.2
Cellular Component:  catalytic step 2 spliceosome; nuclear speck; nucleoplasm; nucleus; spliceosomal complex; U2 snRNP; U2-type precatalytic spliceosome
Molecular Function:  metal ion binding; nucleic acid binding; RNA binding; zinc ion binding
Biological Process:  mRNA processing; mRNA splicing, via spliceosome; RNA splicing; U2-type prespliceosome assembly
Reference #:  Q9D554 (UniProtKB)
Alt. Names/Synonyms: 4930512K19Rik; 60kD; 60kDa; MGC103282; OTTMUSP00000009510; SAP 61; Sap61; Sf3a3; SF3a60; Spliceosome-associated protein 61; Splicing factor 3A subunit 3; splicing factor 3a, subunit 3
Gene Symbols: Sf3a3
Molecular weight: 58,842 Da
Basal Isoelectric point: 5.23  Predict pI for various phosphorylation states
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SF3A3

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene