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PLD2
May have a role in signal-induced cytoskeletal regulation and/or endocytosis. Belongs to the phospholipase D family. Ubiquitous. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.1.4.4; Lipid Metabolism - ether lipid; Lipid Metabolism - glycerophospholipid; Motility/polarity/chemotaxis; Phospholipase |
| Chromosomal Location of Human Ortholog: 17p13.2 |
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Cellular Component:
endoplasmic reticulum membrane; plasma membrane; presynapse
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Molecular Function:
N-acylphosphatidylethanolamine-specific phospholipase D activity; phosphatidylinositol binding; phospholipase D activity; protein binding
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Biological Process:
cytoskeleton organization; Fc-gamma receptor signaling pathway involved in phagocytosis; inositol lipid-mediated signaling; lipid catabolic process; phosphatidic acid biosynthetic process; small GTPase mediated signal transduction; synaptic vesicle recycling
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Reference #:
O14939
(UniProtKB)
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Alt. Names/Synonyms: Choline phosphatase 2; hPLD2; Phosphatidylcholine-hydrolyzing phospholipase D2; Phospholipase D2; PLD 2; PLD1C; PLD2
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Gene Symbols: PLD2
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Molecular weight:
105,987 Da
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Basal Isoelectric point:
7.41
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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