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TAF15
RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II). Belongs to the RRM TET family. Ubiquitous. Observed in all fetal and adult tissues. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Oncoprotein; RNA-binding; Translation |
| Chromosomal Location of human Ortholog: 17q12 |
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Cellular Component:
cytoplasm; nucleolus; nucleoplasm; nucleus
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Molecular Function:
DNA binding; metal ion binding; mRNA 3'-UTR binding; protein binding; RNA binding; transcription coregulator activity
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Biological Process:
DNA-templated transcription; mRNA stabilization; positive regulation of DNA-templated transcription; RNA splicing
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Disease: Chondrosarcoma, Extraskeletal Myxoid
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Reference #:
Q92804
(UniProtKB)
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Alt. Names/Synonyms: 68 kDa TATA-binding protein-associated factor; hTAFII68; Npl3; RBP56; RBP56/CSMF fusion; RNA-binding protein 56; TAF(II)68; TAF15; TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa; TAF2N; TAFII68; TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56); TATA box-binding protein-associated factor 2N (RNA-binding protein 56); TATA-binding protein-associated factor 2N; TATA-box binding protein associated factor 15; TBP-associated factor 15
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Gene Symbols: TAF15
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Molecular weight:
61,830 Da
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Basal Isoelectric point:
8.04
Predict pI for various phosphorylation states
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CST Pathways:
Protein Acetylation
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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