TAF15 RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II). Belongs to the RRM TET family. Ubiquitous. Observed in all fetal and adult tissues. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Oncoprotein; RNA-binding; Translation
Chromosomal Location of Human Ortholog: 17q12
Cellular Component:  cytoplasm; nucleoplasm; nucleus
Molecular Function:  DNA binding; metal ion binding; protein binding
Biological Process:  positive regulation of transcription, DNA-templated; regulation of signal transduction by p53 class mediator; transcription by RNA polymerase II; transcription initiation from RNA polymerase II promoter
Disease: Chondrosarcoma, Extraskeletal Myxoid
Reference #:  Q92804 (UniProtKB)
Alt. Names/Synonyms: 68 kDa TATA-binding protein-associated factor; hTAFII68; Npl3; RBP56; RBP56/CSMF fusion; RNA-binding protein 56; TAF(II)68; TAF15; TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa; TAF2N; TAFII68; TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56); TATA box-binding protein-associated factor 2N (RNA-binding protein 56); TATA-binding protein-associated factor 2N; TATA-box binding protein associated factor 15; TBP-associated factor 15
Gene Symbols: TAF15
Molecular weight: 61,830 Da
Basal Isoelectric point: 8.04  Predict pI for various phosphorylation states
CST Pathways:  Protein Acetylation
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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TAF15

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein