ITPKA Belongs to the inositol phosphokinase (IPK) family. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - inositol phosphate; EC; Kinase, lipid; Motility/polarity/chemotaxis
Chromosomal Location of human Ortholog: 15q15.1
Cellular Component:  cytosol; dendritic spine
Molecular Function:  ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; inositol-1,4,5-trisphosphate 3-kinase activity; Rac GTPase binding
Biological Process:  actin cytoskeleton organization; dendritic spine maintenance; inositol metabolic process; inositol phosphate biosynthetic process; inositol phosphate metabolic process; positive regulation of dendritic spine morphogenesis; protein phosphorylation; regulation of synaptic plasticity; signal transduction
Reference #:  P23677 (UniProtKB)
Alt. Names/Synonyms: Inositol 1,4,5-trisphosphate 3-kinase A; Inositol-trisphosphate 3-kinase A; InsP 3-kinase A; IP3 3-kinase A; IP3-3KA; IP3K A; IP3KA; ITPKA
Gene Symbols: ITPKA
Molecular weight: 51,009 Da
Basal Isoelectric point: 7.59  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB