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NUDC
Plays a role in neurogenesis and neuronal migration. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation. Belongs to the nudC family. Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart. Note: This description may include information from UniProtKB.
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| Protein type: Cell cycle regulation; Cytoskeletal |
| Chromosomal Location of mouse Ortholog: 4|4 D2.3 |
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Cellular Component:
cytoplasm; cytoskeleton; cytosol; microtubule; midbody; mitotic spindle; nucleus
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Molecular Function:
protein binding; unfolded protein binding
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Biological Process:
cell cycle; cell division; mitotic metaphase plate congression; mitotic spindle organization; nuclear migration; protein folding
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Reference #:
O35685
(UniProtKB)
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Alt. Names/Synonyms: nuclear distribution gene C homolog; nuclear distribution gene C homolog (Aspergillus); Nuclear distribution protein C homolog; Nuclear migration protein nudC; Nud; Nudc; nudC nuclear distribution protein; OTTMUSP00000011954; SIG-92; Sil; Silg92; Silica-induced gene 92 protein
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Gene Symbols: Nudc
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Molecular weight:
38,358 Da
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Basal Isoelectric point:
5.17
Predict pI for various phosphorylation states
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