TESK2 a TKL kinase of the LISK family. Predominantly expressed in testis and prostate. The developmental expression pattern in the testis suggests an important role in meitoic stages and/or early stages of spermiogenesis. Three alternatively spliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.12.1; Kinase, protein; LISK family; Protein kinase, Ser/Thr (non-receptor); Protein kinase, TKL; TESK subfamily; TKL group
Chromosomal Location of Human Ortholog: 4|4 D1
Cellular Component:  cytoplasm; nuclear body; nucleoplasm; nucleus
Molecular Function:  ATP binding; kinase activity; metal ion binding; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; transferase activity
Biological Process:  actin cytoskeleton organization; focal adhesion assembly; phosphorylation; protein amino acid phosphorylation
Reference #:  Q8VCT9 (UniProtKB)
Alt. Names/Synonyms: Dual specificity testis-specific protein kinase 2; MGC29168; OTTMUSP00000010191; Tesk2; Testicular protein kinase 2; testis-specific kinase 2
Gene Symbols: Tesk2
Molecular weight: 63,470 Da
Basal Isoelectric point: 6.85  Predict pI for various phosphorylation states
CST Pathways:  Microtubule Dynamics
Select Structure to View Below

TESK2

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene