SLC18A3 Involved in acetylcholine transport into synaptic vesicles. Belongs to the major facilitator superfamily. Vesicular transporter family. Peripheral and central cholinergic nervous systems. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 16p16
Cellular Component:  AP-1 adaptor complex; AP-2 adaptor complex; axon; axon terminus; cholinergic synapse; cytoplasm; cytoplasmic vesicle; integral component of membrane; integral component of synaptic vesicle membrane; neuromuscular junction; neuron projection; perikaryon; synaptic vesicle; terminal bouton
Molecular Function:  acetylcholine transmembrane transporter activity
Biological Process:  acetylcholine transport; ammonium transmembrane transport; drug transmembrane transport; neurotransmitter loading into synaptic vesicle; transmembrane transport
Reference #:  Q62666 (UniProtKB)
Alt. Names/Synonyms: rVAT; Slc18a3; solute carrier family 18 (vesicular acetylcholine), member 3; solute carrier family 18 (vesicular monoamine) member 3; Solute carrier family 18 member 3; solute carrier family 18, member 3; VAChT; Vat; Vesicular acetylcholine transporter
Gene Symbols: Slc18a3
Molecular weight: 56,537 Da
Basal Isoelectric point: 5.68  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene