Kv-beta2 Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters functional properties of Kv1.4. Forms heteromultimeric complex with alpha subunits. Forms a ternary complex with SQSTM1 and PRKCZ. Belongs to the shaker potassium channel beta subunit family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Channel, potassium
Chromosomal Location of Human Ortholog: 4 E2|4 83.08 cM
Cellular Component:  axon; axon terminus; cell junction; cell projection; cytoplasm; cytoskeleton; cytosol; extrinsic component of cytoplasmic side of plasma membrane; integral component of membrane; juxtaparanode region of axon; membrane; neuron projection; pinceau fiber; plasma membrane; postsynaptic density; potassium channel complex; synapse; voltage-gated potassium channel complex
Molecular Function:  aldo-keto reductase (NADP) activity; ion channel binding; oxidoreductase activity; potassium channel regulator activity; protein binding; voltage-gated ion channel activity; voltage-gated potassium channel activity
Biological Process:  hematopoietic progenitor cell differentiation; ion transport; NADPH oxidation; neuromuscular process; oxidation-reduction process; potassium ion transport; protein heterooligomerization; regulation of ion transmembrane transport; regulation of potassium ion transmembrane transport; regulation of protein localization to cell surface
Reference #:  P62482 (UniProtKB)
Alt. Names/Synonyms: Ckbeta2; F5; I2rf5; K(+) channel subunit beta-2; KCAB2; Kcnab2; Kcnb3; Kv-beta-2; Neuroimmune protein F5; OTTMUSP00000011318; OTTMUSP00000011378; potassium voltage gated channel, shaker related subfamily, beta member 2; potassium voltage-gated channel, shaker-related subfamily, beta member 2; Voltage-gated potassium channel subunit beta-2
Gene Symbols: Kcnab2
Molecular weight: 41,021 Da
Basal Isoelectric point: 9.11  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene